Machraoui A, Schött D, Martin W, Lawo T, Barmeyer J, Ulmer W T
Dtsch Med Wochenschr. 1986 Apr 4;111(14):535-8. doi: 10.1055/s-2008-1068485.
Long-term ECG monitoring was carried out on 36 patients with chronic obstructive airway disease and cor pulmonale. Ventricular extrasystoles were detectable in all patients with greater than 30/h occurring in 13. Multifocal ventricular extrasystoles were seen in 29 patients, couplets in 16, runs in 6 and early (R-on-T) extrasystoles in 8 patients. When the ventricular extrasystoles exceeded 30 per hour the average oxygen partial pressure (paO2), determined in capillary blood, was 59.5 mm Hg, whereas it was higher, 66.4 mm Hg (P less than 0.0125), when there were less than or equal to 30/h. Oxygen (2 l/min) was administered to 13 patients between 20.00 h and 08.00 h and then room-air the following night via a nasal tube. After the administration of oxygen mean paO2 was 72.3 mm Hg and after breathing room-air 62.6 mm Hg (P less than 0.01). During the administration of oxygen, extrasystoles appeared less frequently than after breathing room-air (927 vs 1211; P less than 0.05). These results show that ventricular extrasystoles appear more often with decreasing paO2 and that oxygen therapy can reduce their frequency.
对36例慢性阻塞性气道疾病合并肺心病患者进行了长期心电图监测。所有患者均检测到室性期前收缩，13例患者每小时室性期前收缩超过30次。29例患者出现多源性室性期前收缩，16例出现成对室性期前收缩，6例出现连发，8例出现早期（R波落在T波上）室性期前收缩。当每小时室性期前收缩超过30次时，毛细血管血中测定的平均氧分压（paO2）为59.5 mmHg，而当每小时室性期前收缩小于或等于30次时，平均氧分压较高，为66.4 mmHg（P<0.0125）。13例患者于20:00至08:00期间经鼻导管给予氧气（2 l/min），随后夜间呼吸室内空气。吸氧后平均paO2为72.3 mmHg，呼吸室内空气后为62.6 mmHg（P<0.01）。吸氧期间，室性期前收缩出现的频率低于呼吸室内空气后（927次对1211次；P<0.05）。这些结果表明，随着paO2降低，室性期前收缩出现得更频繁，且氧疗可降低其频率。
