Carson S N, Hunter G C, Palmaz J, Guernsey J M
Am J Surg. 1983 Dec;146(6):774-8. doi: 10.1016/0002-9610(83)90339-2.
Forty-two noninfected femoral anastomotic aneurysms that occurred after aortobifemoral bypass were repaired during a 7 year period. Twenty of these were recurrent aneurysms. In an attempt to define the cause of recurrence, a number of factors were studied including infection, suture failure, graft deterioration, defective graft manufacture, graft dilatation, and arterial degeneration. Five grafts in the primary group failed because of inherent defects in the graft structure. Two lightweight Dacron grafts showed generalized graft dilatation, and three unwrapped expanded polytetrafluoroethylene grafts had linear tears at the anastomosis. We believe that such graft degeneration does not represent a current problem because the polytetrafluoroethylene grafts now used are reinforced, and lightweight Dacron grafts are no longer made. Two primary femoral anastomotic aneurysms resulted from broken polypropylene suture. No infections were found in the primary or recurrent groups of aneurysms. Arterial degeneration adjacent to the anastomosis, consisting of a decrease in wall thickness due to loss of smooth muscle with proliferation of elastic fibers and disruption of elastic laminae, was a consistent finding in the remaining 15 primary femoral anastomotic aneurysms and all recurrent femoral anastomotic aneurysms. In many instances of primary femoral anastomotic aneurysm and in all instances of recurrent aneurysms dilatation of the Dacron graft with secondary arterial degeneration was believed to be the cause of aneurysm formation. Graft dilatation without fiber deterioration is an inherent problem in Dacron grafts and reportedly varies from 10 to 50 percent of the original graft diameter. This dilatation plus the use of initial graft diameters larger than the host artery leads to increased tension at the anastomotic site with subsequent arterial degeneration. For the aforementioned reasons, our current practice and recommendation is that repair of all anastomotic aneurysms be with expanded polytetrafluoroethylene grafts sized to approximate the host artery since its dilatation at sites of arterial pressure is minimal.
在7年期间,对42例主动脉双股动脉搭桥术后发生的非感染性股动脉吻合口动脉瘤进行了修复。其中20例为复发性动脉瘤。为了确定复发原因,研究了许多因素,包括感染、缝线失败、移植物退变、移植物制造缺陷、移植物扩张和动脉退变。初次手术组中有5个移植物因移植物结构的固有缺陷而失败。2个轻质涤纶移植物出现广泛性移植物扩张,3个未包裹的膨体聚四氟乙烯移植物在吻合处有线性撕裂。我们认为,由于现在使用的聚四氟乙烯移植物是加固的,且不再生产轻质涤纶移植物,所以这种移植物退变已不再是当前的问题。2例原发性股动脉吻合口动脉瘤是由聚丙烯缝线断裂所致。在原发性和复发性动脉瘤组中均未发现感染。在其余15例原发性股动脉吻合口动脉瘤和所有复发性股动脉吻合口动脉瘤中,均一致发现吻合口附近的动脉退变,表现为平滑肌丢失导致壁厚变薄,弹性纤维增生,弹性膜破坏。在许多原发性股动脉吻合口动脉瘤病例以及所有复发性动脉瘤病例中,涤纶移植物扩张伴继发性动脉退变被认为是动脉瘤形成的原因。涤纶移植物中,无纤维退变的移植物扩张是一个固有问题,据报道,其扩张幅度为原始移植物直径的10%至50%。这种扩张加上最初使用的移植物直径大于宿主动脉,导致吻合口处张力增加,继而引起动脉退变。基于上述原因,我们目前的做法和建议是,所有吻合口动脉瘤的修复均使用尺寸与宿主动脉相近的膨体聚四氟乙烯移植物,因为其在动脉压力部位的扩张极小。