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无胸腺“裸”(Nu/Nu)以及有胸腺(Nu/+和+/+)的Balb/c小鼠的淋巴结肥大细胞

Lymph node mast cells in athymic "nude" (Nu/Nu) and thymus containing (Nu/+ and +/+) Balb/c mice.

作者信息

Włodarski K, Rose N R, Morrison K

出版信息

Arch Immunol Ther Exp (Warsz). 1983;31(2):177-82.

PMID:6651480
Abstract

Total number of mast cells in popliteal lymph nodes of Balb/c mice is a function of time and Nu gene (complex?) content. The number of mast cells increases with age - in both wild +/+ and in Nu gene (complex?) carriers (Nu/+ and Nu/Nu). The increase in the number of mast cells is faster in the Nu gene carriers than in wild animals +/+ devoid of this gene. In "nude" mice having advanced hepatitis a dramatic increase in the number of lymphoid mast cells was observed. Results obtained deny the importance of thymus in the production of lymphatic mast cells in mice.

摘要

Balb/c小鼠腘窝淋巴结中肥大细胞的总数是时间和Nu基因(复合体?)含量的函数。肥大细胞的数量随年龄增加——在野生型+/+和Nu基因(复合体?)携带者(Nu/+和Nu/Nu)中均如此。Nu基因携带者中肥大细胞数量的增加比缺乏该基因的野生型动物+/+更快。在患有晚期肝炎的“裸”鼠中,观察到淋巴样肥大细胞数量急剧增加。所得结果否定了胸腺在小鼠淋巴肥大细胞产生中的重要性。

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Lymph node mast cells in athymic "nude" (Nu/Nu) and thymus containing (Nu/+ and +/+) Balb/c mice.无胸腺“裸”(Nu/Nu)以及有胸腺(Nu/+和+/+)的Balb/c小鼠的淋巴结肥大细胞
Arch Immunol Ther Exp (Warsz). 1983;31(2):177-82.
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