Cals L, Tubiana N, Lieutaud R, Carcassonne Y
Bull Cancer. 1983;70(4):289-93.
Primary thymic seminoma is a rare germ cell neoplasm histologically identical to testicular seminoma. About 100 cases have been reported in the world literature. The most probable pathogenic theory is abnormal migration of germinal cells from the vitelline sac to the embryonic thymus. Management involves surgery and radiotherapy. The extreme radiosensitivity of the tumor is responsible for a 5-years survival rate of 75 per cent. Thymic seminomas are usually found in young men. We report the case of a 49 year female in whom the combination of surgery and radiotherapy followed by chemotherapy provided excellent results.
原发性胸腺精原细胞瘤是一种罕见的生殖细胞肿瘤，组织学上与睾丸精原细胞瘤相同。世界文献中已报道了约100例病例。最可能的致病理论是生殖细胞从卵黄囊异常迁移至胚胎胸腺。治疗方法包括手术和放疗。肿瘤极高的放射敏感性使得5年生存率达到75%。胸腺精原细胞瘤通常见于年轻男性。我们报告了一例49岁女性患者，手术和放疗联合化疗取得了极佳效果。
