Casan P, Roca J, Sanchis J
Bull Eur Physiopathol Respir. 1983 Nov-Dec;19(6):567-9.
The spirometric response to inhaled salbutamol was assessed in 492 healthy volunteers 6 to 20 yr of age. Mean and standard deviation of the changes, expressed as percentage of prebronchodilator values, were as follows: forced vital capacity (FVC): 1.7 +/- 2.8; forced expiratory volume in one second (FEV1): 3.3 +/- 3.4; (FEV1/FVC): 3.1 +/- 3.2; peak expiratory flow: 6.4 +/- 8.6; maximal mid-expiratory flow: 10.1 +/- 8.8; maximum expiratory flow at 50% of FVC: 8.8 +/- 9.5 and maximum expiratory flow at 25% of FVC: 14.0 +/- 14.7. The changes were significant (p less than 0.005) for all parameters and similar to those observed in adults.
对492名6至20岁的健康志愿者吸入沙丁胺醇后的肺量计反应进行了评估。变化的平均值和标准差，以支气管扩张剂使用前值的百分比表示，如下所示：用力肺活量（FVC）：1.7±2.8；一秒用力呼气量（FEV1）：3.3±3.4；（FEV1/FVC）：3.1±3.2；呼气峰值流速：6.4±8.6；最大呼气中期流速：10.1±8.8；FVC的50%时的最大呼气流量：8.8±9.5和FVC的25%时的最大呼气流量：14.0±14.7。所有参数的变化均具有显著性（p<0.005），且与在成年人中观察到的变化相似。
