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IR absorption spectrophotometric analysis of the complex formed by tetracycline and synthetic hydroxyapatite.

作者信息

Myers H M, Tochon-Danguy H J, Baud C A

出版信息

Calcif Tissue Int. 1983 Sep;35(6):745-9. doi: 10.1007/BF02405117.

DOI:10.1007/BF02405117
PMID:6652549
Abstract

The infrared (IR) spectra of KBr pellet preparations of tetracycline (TC) complexes with hydroxyapatite (HA) indicated that the binding of the antibiotic to bone mineral can occur independently at each of two ligands. The shifts in the IR spectrum occur for the keto-enol ligand of rings B and C and for the tricarbonylmethane grouping of ring A. Analogs that lack one or the other of these groups are able to form complexes with HA in which the common portion resembles that of the parent molecule.

摘要

相似文献

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本文引用的文献

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Effects of demineralizing tetracycline-stained human dentine.脱矿对四环素染色的人牙本质的影响。
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10
Side-effects to antibiotics in cystic fibrosis: dental changes in relation to antibiotic administration.囊性纤维化患者使用抗生素的副作用：与抗生素使用相关的牙齿变化。
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