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高风险群体的扩展操作概念及其在标准制定中的作用。

Expanded operational concept of high risk groups and its role in standard setting.

作者信息

Calabrese E J

出版信息

Environ Health Perspect. 1983 Oct;52:257-60. doi: 10.1289/ehp.8352257.

Abstract

The role of the knowledge of high risk groups in the standard-setting process is examined. The overall conclusion is that many potential high risk segments of the population have not been studied adequately and that this deficiency in our knowledge markedly reduces the ability of decision makers to derive appropriate regulatory decisions by either ignoring the potential health effects or applying potentially excessive and expensive safety factors.

摘要

本文探讨了高危人群知识在标准制定过程中的作用。总体结论是,许多潜在的高危人群尚未得到充分研究,而我们在这方面知识的欠缺显著降低了决策者做出适当监管决策的能力,他们要么忽视潜在的健康影响,要么应用可能过高且昂贵的安全系数。

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本文引用的文献

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Ann N Y Acad Sci. 1974 Nov 29;241(0):605-13. doi: 10.1111/j.1749-6632.1974.tb21917.x.
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Investigation of potential animal models of thalassemia.地中海贫血潜在动物模型的研究。
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