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一家精神病院里的肝炎标志物

Hepatitis markers in a psychiatric institution.

作者信息

Gmelin K, Doerr H W, Middelhoff H, von Ehrlich B, Sann G, Theilmann G, Kommerell B

出版信息

Dev Biol Stand. 1983;54:545-8.

PMID:6653899
Abstract

Hepatitis A and B markers were determined in 714 patients and in 291 members of the staff of a psychiatric institution for adults. The leading diagnosis were psychosis (71.8%), neurosis (17.7%), and oligophrenia (10.6%). Anti-HAV was found in 84.4% of the patients and in 69.2% of the staff. 26.8% of the patients and 19.9% of the staff had at least one HBV marker. The frequency of HBV markers correlated with the age of the patients but not with the duration of the hospitalization. After the exclusion of IgM-anti-HAV, IgM-anti-CMV and IgM-anti-EBV or possible toxic effects, 2.6% of all patients remained as presumable non-A, non-B hepatitis infections. In this study HBV markers were not found in an hyperendemic pattern reported previously in psychiatric institutions.

摘要

对一家成人精神病院的714名患者和291名工作人员进行了甲型和乙型肝炎标志物检测。主要诊断为精神病(71.8%)、神经症(17.7%)和智力发育不全(10.6%)。84.4%的患者和69.2%的工作人员检测出抗甲型肝炎病毒。26.8%的患者和19.9%的工作人员至少有一项乙型肝炎病毒标志物。乙型肝炎病毒标志物的出现频率与患者年龄相关,但与住院时间无关。排除IgM抗甲型肝炎病毒、IgM抗巨细胞病毒和IgM抗EB病毒或可能的毒性作用后,所有患者中有2.6%被推定为非甲非乙型肝炎感染。在本研究中,未发现精神病院先前报告的乙型肝炎病毒标志物的高度流行模式。

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[Is it necessary to investigate anti-hepatitis A virus (HAV) IgM antibodies when the hepatic enzymogram is normal?].当肝功能酶谱正常时,有必要检测抗甲型肝炎病毒(HAV)IgM抗体吗?
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