Gmelin K, Doerr H W, Bommer J, Ritz E, Sann G, Theilmann G, von Ehrlich B, Kommerell B
Dev Biol Stand. 1983;54:483-6.
Episodes of presumable non-A, non-B hepatitis were determined among hemodialysis patients during a two year period as well as possible secondary infections in household contacts. We determined hepatitis A and B markers by commercial RIA kits, and IgM-anti-CMV and IgM-anti-EBV by ELISA techniques. 154 dialysis patients, 118 relatives of patients, and 42 members of the staff were included in the study. 71% of the center dialysis patients, 63% of the home dialysis patients, 50% of the staff, and 19% of the relatives were HBV marker positive. Spouses of patients more often had HBV markers than other relatives. Anti-HAV was highly prevalent both in center patients (98.8%) and in home dialysis patients (83.3%). The incidence of IgM-anti-CMV was marked in home dialysis patients (15.5%). During a two year period, 9% of all dialysis patients had an episode of presumable non-A, non-B hepatitis. As compared to previous data in the same dialysis centers, there is a change in the epidemiology of hepatitis.
在两年时间里，我们确定了血液透析患者中可能的非甲非乙型肝炎发作情况以及家庭接触者中可能的继发感染情况。我们通过商用放射免疫分析试剂盒检测甲型和乙型肝炎标志物，通过酶联免疫吸附测定技术检测抗巨细胞病毒 IgM 和抗 Epstein-Barr 病毒 IgM。154 名透析患者、118 名患者亲属和 42 名工作人员纳入了研究。中心透析患者中 71%、家庭透析患者中 63%、工作人员中 50%以及亲属中 19%的乙型肝炎病毒标志物呈阳性。患者的配偶比其他亲属更常出现乙型肝炎病毒标志物。抗甲型肝炎病毒在中心患者（98.8%）和家庭透析患者（83.3%）中都非常普遍。抗巨细胞病毒 IgM 在家庭透析患者中的发生率显著（15.5%）。在两年时间里，所有透析患者中有 9%发生了可能的非甲非乙型肝炎发作。与同一透析中心之前的数据相比，肝炎的流行病学情况发生了变化。
