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用氟化物和镉评估51铬释放细胞毒性测定法。

51Cr release cytotoxicity assay evaluated with fluoride and cadmium.

作者信息

Holland R I

出版信息

Agents Actions. 1978 Apr;8(3):311-4. doi: 10.1007/BF01966621.

DOI:10.1007/BF01966621
PMID:665443
Abstract

The sensitivity of the 51Cr release assay was evaluated with two known cytotoxic agents; fluoride and cadmium. The sensitivity was far less than that of other assays, e.g. growth inhibition of cultured cells, and additional a two-peaked dose-response curve was found with cadmium.

摘要

用两种已知的细胞毒性剂氟化物和镉评估了51铬释放试验的敏感性。其敏感性远低于其他试验，例如培养细胞的生长抑制试验，并且发现镉的剂量反应曲线呈双峰状。

相似文献

1
51Cr release cytotoxicity assay evaluated with fluoride and cadmium.用氟化物和镉评估51铬释放细胞毒性测定法。
Agents Actions. 1978 Apr;8(3):311-4. doi: 10.1007/BF01966621.
2
Influence of fluoride on the uptake of 51Cr-chromate by human erythrocytes.氟化物对人红细胞摄取51Cr-铬酸盐的影响。
J Inorg Biochem. 1979 Aug;11(1):1-6. doi: 10.1016/s0162-0134(00)80047-1.
3
Validity of chromium-51 labelling of human erythrocytes as an assay for their survival after photodynamic therapy in vitro for blood sterilization.
Int J Radiat Biol. 1993 May;63(5):651-3. doi: 10.1080/09553009314450841.
4
Fluoride inhibition of erythrocyte metabolism as a function of cellular P.氟化物对红细胞代谢的抑制作用与细胞内磷的关系
Biochim Biophys Acta. 1966 Aug 24;124(2):421-3. doi: 10.1016/0304-4165(66)90213-3.
5
Effects of fluoride and cadmium co-exposure on bone in male rats.氟和镉联合暴露对雄性大鼠骨骼的影响。
Biol Trace Elem Res. 2013 Sep;154(3):396-402. doi: 10.1007/s12011-013-9750-4. Epub 2013 Jul 20.
6
Uptake of 51Cr(VI) by human erythrocytes: evidence for a carrier-mediated transport mechanism.人红细胞对51Cr(VI)的摄取：载体介导转运机制的证据
Sci Total Environ. 1988 Jun 1;71(3):561-6. doi: 10.1016/0048-9697(88)90237-9.
7
The use of 51Cr for assessing cytotoxicity in an in vitro bioassay for inhibin.
Mol Cell Endocrinol. 1982 Apr;26(1-2):119-27. doi: 10.1016/0303-7207(82)90010-7.
8
51Cr-uptake assay. A sensitive and reliable method to quantitate cell viability and cell death.51铬摄取试验。一种用于定量细胞活力和细胞死亡的灵敏且可靠的方法。
J Immunol Methods. 1987 May 4;99(1):77-82. doi: 10.1016/0022-1759(87)90034-2.
9
Sodium pyruvate inhibits the spontaneous release of 51Cr from RBC in chromium release assays.在铬释放试验中，丙酮酸钠可抑制红细胞中51Cr的自发释放。
J Immunol Methods. 1990 May 8;129(1):139-41. doi: 10.1016/0022-1759(90)90431-t.
10
51Cr-labeled human hepatocytes as target cells for cytotoxicity mediated by freshly isolated liver-infiltrating lymphocytes.以51铬标记的人肝细胞作为由新鲜分离的肝浸润淋巴细胞介导的细胞毒性作用的靶细胞。
J Immunol Methods. 1993 Aug 26;164(1):69-77. doi: 10.1016/0022-1759(93)90277-e.

本文引用的文献

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The tagging of red cells and plasma proteins with radioactive chromium.用放射性铬标记红细胞和血浆蛋白。
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QUANTITATIVE TITRATIONS OF MOUSE H-2 ANTIBODIES USING CR-51-LABELLED TARGET CELLS.使用铬-51标记靶细胞对小鼠H-2抗体进行定量滴定
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Site of binding of chromium-51 to haemoglobin.铬-51与血红蛋白的结合位点。
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Isotope-labelled alpha-amino-isobutyric acid as an indicator in cytotoxicity tests.同位素标记的α-氨基异丁酸作为细胞毒性试验的指示剂。
Acta Pathol Microbiol Scand C. 1977 Feb;85(1):73-7. doi: 10.1111/j.1699-0463.1977.tb03613.x.
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Biologic evaluation of filling materials. A comparison of results using cell culture techniques, implantation tests and pulp studies.
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