慢性前列腺炎、沙眼衣原体与不孕不育

Chronic prostatitis, chlamydia trachomatis and infertility.

作者信息

Suominen J, Grönroos M, Terho P, Wichmann L

出版信息

Int J Androl. 1983 Oct;6(5):405-13. doi: 10.1111/j.1365-2605.1983.tb00555.x.

DOI:10.1111/j.1365-2605.1983.tb00555.x

Abstract

Seventy-one infertile men were studied for the presence of seminal leucocytosis, and for the levels of acid phosphatase activity and Chlamydia trachomatis antibodies of IgA class using a novel method of solid-phase radioimmunoassay. The findings were compared with those of 56 fertile men. Chlamydial IgA antibodies were found in the semen of 51.1% of infertile men with seminal leucocytosis and decreased seminal acid phosphatase activity, i.e. those defined as having asymptomatic chronic prostatitis. This frequency was significantly higher than among fertile men (23.2%, P less than 0.01) and those infertile men who had no signs of chronic prostatitis (26.9%, P less than 0.05). It is concluded that Chlamydia trachomatis seems to be a common cause of prostatitis and may also interfere with fertility.

摘要

对71名不育男性进行了研究，以检测其精液中是否存在白细胞增多症，并采用一种新型固相放射免疫测定法检测其酸性磷酸酶活性水平和IgA类沙眼衣原体抗体。将研究结果与56名生育能力正常的男性进行比较。在精液白细胞增多且精液酸性磷酸酶活性降低（即被定义为患有无症状慢性前列腺炎）的不育男性中，51.1%的人精液中发现了衣原体IgA抗体。这一频率显著高于生育能力正常的男性（23.2%，P<0.01）和那些没有慢性前列腺炎迹象的不育男性（26.9%，P<0.05）。研究得出结论，沙眼衣原体似乎是前列腺炎的常见病因，也可能影响生育能力。