Schmidt-Bleek F, Lange A W
Regul Toxicol Pharmacol. 1983 Dec;3(4):311-9. doi: 10.1016/0273-2300(83)90002-8.
The German Chemicals Act of 1980 which came into force on January 1, 1982 aims to protect man and the environment from the unwanted effects of chemicals. As is true for all quality control legislation for chemical products, the scientific goal is to simulate under controlled conditions agent-target interactions as are likely to occur and to estimate the probability of agents reaching the target: the hazard of a chemical is a function of exposure and effect considerations. Beyond attempting to control chemical products, it may soon become necessary to consider the totality of all substances entering the environment as a consequence of technological activities: raw material extraction, production, transport, storage, and waste disposal. The paper aims at identifying important areas of research where it is felt that more systematic knowledge could help to render administrative decision-making processes more transparent, more cost effective, and bring them better in line with the legal mandate of protecting the environment from dangerous chemicals. While the paper focuses on problems surrounding the multitude of "existing chemicals," many an item discussed is significant also for the preventive protection from dangerous "new chemicals."
1980年的德国《化学品法》于1982年1月1日生效，旨在保护人类和环境免受化学品的有害影响。与所有化学品质量控制立法一样，科学目标是在可控条件下模拟可能发生的药剂与靶标的相互作用，并估计药剂到达靶标的概率：化学品的危害是暴露和效应考量的函数。除了试图控制化学产品外，可能很快就有必要考虑因技术活动而进入环境的所有物质的总体情况：原材料提取、生产、运输、储存和废物处理。本文旨在确定重要的研究领域，人们认为在这些领域，更系统的知识有助于使行政决策过程更加透明、更具成本效益，并使其更好地符合保护环境免受危险化学品危害的法律要求。虽然本文关注围绕众多“现有化学品”的问题，但所讨论的许多内容对于预防危险“新化学品”也具有重要意义。
