Nagase M, Tanimura H, Setoyama M, Hikasa Y
Am J Surg. 1978 Jun;135(6):788-90. doi: 10.1016/0002-9610(78)90165-4.
A collective review of 2,144 patients operated on for cholelithiasis during the last twenty-two months has shown that younger Japanese adults have predominantly cholesterol stones in their gallbladders and that elderly persons still frequently have bilirubin stones not only in their gallbladders but also in their common bile ducts. Recent westernization of dietary habits in Japan is considered to be the most probable factor causing the increased incidence of cholesterol stones. The decreased incidence of bilirubin stones is considered to be caused by the decreased incidence of biliary infection and increased intake of proteins in food.
对过去22个月内接受胆结石手术的2144例患者进行的综合回顾显示,较年轻的日本成年人胆囊中主要是胆固醇结石,而老年人不仅在胆囊中,而且在胆总管中仍经常有胆红素结石。日本近期饮食习惯的西化被认为是导致胆固醇结石发病率增加的最可能因素。胆红素结石发病率的下降被认为是由胆道感染发病率的下降和食物中蛋白质摄入量的增加所致。