Arnaud J, Gutiérrez N, Vergnes H
Acta Physiol Lat Am. 1983;33(1):7-14.
Glucose consumption by anaerobic glycolysis and the pentose pathway were studied in two Aymara populations living at different altitudes (3 600 m and 450 m). The measurements were made both with and without methylene blue. We observed a Pasteur effect for both pathways which may explain the increase in 2-3 DPG and ATP levels found in blood samples from people living at high altitudes. The results in the presence of methylene blue showed a reduced activity of the methaemoglobin reductase system in the high altitude group which may be partly responsible for their increased levels of methaemoglobin.
对生活在不同海拔高度（3600米和450米）的两个艾马拉人群进行了无氧糖酵解和戊糖途径的葡萄糖消耗研究。测量在有和没有亚甲蓝的情况下进行。我们观察到这两种途径都存在巴斯德效应，这可能解释了在高海拔地区人群血液样本中发现的2,3-二磷酸甘油酸（2-3 DPG）和三磷酸腺苷（ATP）水平升高的现象。在有亚甲蓝存在的情况下，高海拔组的高铁血红蛋白还原酶系统活性降低，这可能部分导致了他们高铁血红蛋白水平的升高。
