Huysmans F T, Sluiter H E, Thien T A, Koene R A
Br J Clin Pharmacol. 1983 Dec;16(6):725-7. doi: 10.1111/j.1365-2125.1983.tb02250.x.
Ten patients with a hypertensive crisis and a decreased renal function were treated with 10 (n = 7) or 20 (n = 3) mg nifedipine sublingually. Blood pressure was reduced in 60 min from 211 +/- 4/134 +/- 5 to 172 +/- 6/107 +/- 6 mm Hg. The decrease of blood pressure was accompanied by a rise in heart rate from 83 +/- 6 to 98 +/- 5 beats/min. In all seven patients with an encephalopathy signs of this complication were reduced. No serious side-effects were observed.
10例高血压危象且肾功能减退的患者接受了10毫克（n = 7）或20毫克（n = 3）硝苯地平舌下含服治疗。60分钟内血压从211±4/134±5毫米汞柱降至172±6/107±6毫米汞柱。血压下降的同时心率从83±6次/分钟升至98±5次/分钟。在所有7例患有脑病的患者中，该并发症的体征均有所减轻。未观察到严重副作用。
