Miura M, Takayama K
Brain Res. 1983 Dec 12;288(1-2):389-92. doi: 10.1016/0006-8993(83)90126-9.
By applying the specific opiate antagonist naloxone to the lateral portion of the nucleus tractus solitarii of the cat, we not only rapidly inhibited the evoked field potentials elicited by stimulation of the ipsilateral carotid sinus nerve (CSN), but also blocked hypotension and bradycardia induced by CSN stimulation. These findings suggest that some opiates may be neurotransmitters of the primary myelinated fibers of the CSN which mediate hypotension and bradycardia.
通过将特定的阿片类拮抗剂纳洛酮应用于猫孤束核的外侧部分，我们不仅迅速抑制了刺激同侧颈动脉窦神经（CSN）所诱发的场电位，还阻断了CSN刺激所诱导的低血压和心动过缓。这些发现表明，某些阿片类物质可能是CSN初级有髓纤维的神经递质，它们介导低血压和心动过缓。
