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小猫坐骨神经切除术后无髓鞘L7背根轴突的选择性丢失

Preferential loss of unmyelinated L7 dorsal root axons following sciatic nerve resection in kittens.

作者信息

Aldskogius H, Risling M

出版信息

Brain Res. 1983 Dec 19;289(1-2):358-61. doi: 10.1016/0006-8993(83)90042-2.

Abstract

Some time following sciatic nerve resection in kittens the number of L7 spinal ganglion neurons appears to have decreased more than the number of L7 dorsal root axons, and the proportion of unmyelinated axons is unchanged. The present results show that removal of the sciatic neuroma results in a clearly subnormal proportion of unmyelinated axon profiles. This indicates that recurrent sprouts from the neuroma had entered the dorsal root and that spinal ganglion neurons with unmyelinated axons are preferentially lost after axotomy in kittens.

摘要

在小猫坐骨神经切除后的一段时间里,L7脊髓神经节神经元数量的减少似乎比L7背根轴突数量的减少更多,且无髓鞘轴突的比例没有变化。目前的结果表明,切除坐骨神经瘤会导致无髓鞘轴突轮廓的比例明显低于正常水平。这表明神经瘤的再生芽已进入背根,并且在小猫进行轴突切断术后,具有无髓鞘轴突的脊髓神经节神经元优先丢失。

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