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坐骨神经挤压对幼猫L7脊髓神经根和背根神经节的影响。

Effects of sciatic nerve crush on the L7 spinal roots and dorsal root ganglia in kittens.

作者信息

Risling M, Aldskogius H, Hildebrand C

出版信息

Exp Neurol. 1983 Jan;79(1):176-87. doi: 10.1016/0014-4886(83)90389-8.

DOI:10.1016/0014-4886(83)90389-8
PMID:6822253
Abstract

The number and size distribution of axons and neurons were examined in the L7 spinal roots and ganglia of kittens 14 to 220 days after early postnatal sciatic nerve crush. The results show that motoraxons in the ventral root as well as axons and perikarya of sensory neurons in the dorsal root remained growth-retarded throughout the examined period. This was most evident in the dorsal root. Both ventral and dorsal roots showed some loss of myelinated axons, but this was only half that previously observed after sciatic nerve resection. Whereas in the dorsal roots and dorsal root ganglia the loss seemed to be nonselective with respect to size, axons in the gamma range were primarily affected in the ventral roots. In the dorsal roots the proportion of unmyelinated axons was comparable with controls but in the ventral roots it was somewhat elevated. In most cases the loss of dorsal root ganglion neurons was relatively greater than the decrease of dorsal root axons.

摘要

在出生后早期坐骨神经挤压后14至220天的小猫的L7脊髓神经根和神经节中,检查了轴突和神经元的数量及大小分布。结果显示,在整个检查期间,腹侧根中的运动轴突以及背侧根中感觉神经元的轴突和胞体仍生长迟缓。这在背侧根中最为明显。腹侧根和背侧根均显示出一些有髓轴突的丢失,但这仅是先前坐骨神经切除术后观察到的一半。在背侧根和背侧根神经节中,这种丢失似乎与大小无关,而腹侧根中γ范围内的轴突主要受到影响。在背侧根中,无髓轴突的比例与对照组相当,但在腹侧根中则有所升高。在大多数情况下,背侧根神经节神经元的丢失相对大于背侧根轴突的减少。

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Exp Neurol. 1983 Jan;79(1):176-87. doi: 10.1016/0014-4886(83)90389-8.
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