Harker G J, Zbroja R A, Wass J, Vincent P C, Stephens F O
Exp Hematol. 1983 Nov;11(10):1037-41.
The distributions of cells in each of the phases of the cell cycle, determined by flow cytometry (FCM), were compared in multiple marrow trephine biopsy samples from 3 sites (both iliac bones and sternum) in 5 sheep. Within any one animal no significant differences could be found between the proportions of cells in the G0/G1, S or G2 + M phases of the cycle from different sites. Differences between animals were detected and these were consistent for any of the sites sampled. We conclude that the proliferative characteristics of marrow cells as determined by FCM in any one animal at one time are comparable at anatomically distinct marrow sites, and that a sample from one site is representative of the whole.
通过流式细胞术（FCM）测定，比较了5只绵羊3个部位（双侧髂骨和胸骨）的多个骨髓环钻活检样本中处于细胞周期各阶段的细胞分布情况。在任何一只动物体内，不同部位处于细胞周期G0/G1、S或G2+M期的细胞比例之间均未发现显著差异。检测到了动物之间的差异，且这些差异在任何采样部位都是一致的。我们得出结论，在任何一只动物体内，通过FCM测定的骨髓细胞增殖特征在解剖学上不同的骨髓部位是可比的，并且来自一个部位的样本代表了整体情况。
