人类核DNA中存在线粒体DNA样序列。
Presence of mitochondrial-DNA-like sequences in the human nuclear DNA.
作者信息
Tsuzuki T, Nomiyama H, Setoyama C, Maeda S, Shimada K
出版信息
Gene. 1983 Nov;25(2-3):223-9. doi: 10.1016/0378-1119(83)90226-3.
Two lambda phage clones carrying contiguous human nuclear DNA sequences with extensive homology to non-contiguous human mitochondrial 16S ribosomal RNA sequences were isolated from a human gene library. The one clone carried mitochondrial-DNA(mtDNA)-like sequences flanked with two kinds of repetitive nuclear DNA sequences and the other carried mtDNA-like sequences, between unique nuclear DNA sequences and repetitive DNA sequences of Alu-family. These results demonstrate that mtDNA-like sequences are present in human nuclear DNA.
从一个人类基因文库中分离出了两个λ噬菌体克隆，它们携带的人类核DNA序列与不连续的人类线粒体16S核糖体RNA序列具有广泛的同源性。其中一个克隆携带的线粒体DNA（mtDNA）样序列两侧是两种重复的核DNA序列，另一个克隆携带的mtDNA样序列位于独特的核DNA序列和Alu家族的重复DNA序列之间。这些结果表明人类核DNA中存在mtDNA样序列。
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