水消费者接触嗜温放线菌。
Exposure of water consumers to mesophilic actinomycetes.
作者信息
Ojanen T H, Katila M L, Mäntyjärvi R, Seppänen H, Muittari A, Kuusisto P, Virtanen P
出版信息
J Hyg (Lond). 1983 Dec;91(3):535-41. doi: 10.1017/s0022172400060587.
In autumn 1978 an epidemic of respiratory disease resembling allergic alveolitis occurred in a small Finnish community. The disease was caused by repeated exposures to tap water aerosol. The raw water of the community and the sand filters of the purification system were heavily contaminated with mesophilic actinomycetes. Fourteen different strains of actinomycetes were isolated. Exposed persons with and without symptoms as well as unexposed control persons were tested for antibodies against five of these actinomycetes and against Enterobacter agglomerans. Both the exposed and the control persons had antibodies to actinomycetes but the exposed persons had antibodies against more actinomycete strains than the control persons. Precipitating antibodies against E. agglomerans were also found in control persons as well as in patients. There was a significant difference between the patients and the exposed healthy persons in bacterial agglutination tests with flagellar antigen of one E. agglomerans strain. However, the role of mesophilic actinomycetes and E. agglomerans in the aetiology of the disease could not be firmly established.
1978年秋，芬兰一个小社区爆发了一场类似过敏性肺泡炎的呼吸道疾病疫情。该病是由反复接触自来水气溶胶所致。该社区的原水和净化系统的砂滤器被嗜温放线菌严重污染。分离出了14种不同的放线菌菌株。对有症状和无症状的暴露者以及未暴露的对照者进行了针对其中5种放线菌和成团肠杆菌的抗体检测。暴露者和对照者均有针对放线菌的抗体，但暴露者针对的放线菌菌株比对照者更多。在对照者和患者中也发现了针对成团肠杆菌的沉淀抗体。在对一种成团肠杆菌菌株的鞭毛抗原进行的细菌凝集试验中，患者和暴露的健康人之间存在显著差异。然而，嗜温放线菌和成团肠杆菌在该病病因学中的作用尚未能明确确立。
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