Sink J D, Kramer S A, Copeland D D, Seigler H F
Ann Surg. 1978 Jul;188(1):53-9. doi: 10.1097/00000658-197807000-00009.
Cloacogenic carcinoma is a rare tumor of the anorectal region originating from a persistant remnant of the cloacal membrane of the embryo. The tumor accounts for 2-3% of anorectal carcinomas and occurs more than twice as often in women. Most tumors present as fungating or ulcerating lesions, but the tumor may arise in anal ducts and present as a submucosal mass. Wide abdominoperineal resection is the treatment of choice with a five year survival of 50%. Metastases occurs to the inguinal lymph nodes in more than 50% of the patients at sometime during the course of the disease with distant metastases occuring most commonly to liver and lungs.
泄殖腔源癌是一种发生于肛管直肠区域的罕见肿瘤，起源于胚胎泄殖腔膜的残留部分。该肿瘤占肛管直肠癌的2% - 3%，女性发病率是男性的两倍多。大多数肿瘤表现为蕈状或溃疡性病变，但也可能起源于肛管并表现为黏膜下肿块。广泛的腹会阴联合切除术是首选治疗方法，五年生存率为50%。超过50%的患者在病程中的某个时候会发生腹股沟淋巴结转移，远处转移最常见于肝脏和肺部。
