Kawatani M, Lowe I P, Nadelhaft I, Morgan C, De Groat W C
Neurosci Lett. 1983 Dec 11;42(3):311-6. doi: 10.1016/0304-3940(83)90280-x.
Immunohistochemical studies revealed that vasoactive intestinal polypeptide (VIP) is localized primarily to sacral segments of the cat's spinal cord. VIP is most prominent in afferent axons and terminals in Lissauer's tract and in lateral laminae I and V of the dorsal horn. The distribution of VIP terminals is very similar to that of visceral afferent projections identified by horseradish peroxidase. Dye-tracing experiments combined with immunohistochemistry demonstrated that VIP is located in visceral afferent perikarya in the sacral dorsal root ganglia and also in terminals in the sacral autonomic nucleus. These observations suggest that VIP is a neurotransmitter in afferent projections from the pelvic viscera.
免疫组织化学研究表明，血管活性肠肽（VIP）主要定位于猫脊髓的骶段。VIP在脊髓背外侧束的传入轴突和终末以及背角的I层和V层外侧最为显著。VIP终末的分布与辣根过氧化物酶鉴定的内脏传入投射的分布非常相似。染料追踪实验与免疫组织化学相结合表明，VIP位于骶背根神经节的内脏传入神经元胞体以及骶自主核的终末中。这些观察结果表明，VIP是来自盆腔脏器的传入投射中的一种神经递质。
