大鼠肝脏粪卟啉原氧化酶活性定位于线粒体膜间隙的证据。
Evidence that the coproporphyrinogen oxidase activity of rat liver is situated in the intermembrane space of mitochondria.
作者信息
Elder G H, Evans J O
出版信息
Biochem J. 1978 May 15;172(2):345-7. doi: 10.1042/bj1720345.
Abstract
Preferential rupture of the outer membrane of mitochondria from rat liver releases coproporphyrinogen oxidase in parallel with components of the intermembrane space. Coproporphyrinogen III enters the mitochondrion through the freely-permeable outer membrane. Either protoporphyrinogen IX or protoporphyrin IX must then cross the inner membrane before haem synthesis can be completed.
摘要
大鼠肝脏线粒体外膜的优先破裂会与膜间隙成分同时释放粪卟啉原氧化酶。粪卟啉原III通过可自由通透的外膜进入线粒体。然后，在血红素合成完成之前，原卟啉原IX或原卟啉IX必须穿过内膜。
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