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培养的人细胞对伴刀豆球蛋白A反应的组织特异性

Tissue-specificity of reactivity to concanavalin-A of human cells in culture.

作者信息

Ban S, Iida S

出版信息

Exp Gerontol. 1983;18(4):293-301. doi: 10.1016/0531-5565(83)90040-2.

DOI:10.1016/0531-5565(83)90040-2
PMID:6667720
Abstract

Concanavalin-A (Con-A) reactivity was studied to identify the tissue-specificity of cells established from various normal human tissues. Cells were treated with Con-A-labelled human red blood cells (C-RBC). C-RBC was not absorbed on the cells derived from the bone marrow, skin and liver. Lung-derived fibroblast cells showed weak C-RBC adsorption. Kidney-derived cells showed epithelial morphology and easily adsorbed C-RBC. These suggest that a large number of Con-A receptors exists on the membrane surface of kidney cells.

摘要

研究了伴刀豆球蛋白A(Con-A)反应性,以确定从各种正常人体组织建立的细胞的组织特异性。细胞用Con-A标记的人红细胞(C-RBC)处理。C-RBC未吸附在源自骨髓、皮肤和肝脏的细胞上。肺来源的成纤维细胞显示出较弱的C-RBC吸附。肾来源的细胞呈现上皮形态,且易于吸附C-RBC。这些表明肾细胞膜表面存在大量Con-A受体。

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