Wiernik A, Jarstrand C, Angelin B
J Clin Lab Immunol. 1983 Aug;11(4):207-8.
Different plasma lipoprotein fractions in physiological concentrations have opposite effects on the phagocytosis and migration of human neutrophilic granulocytes. Preincubation for half an hour with very low density lipoproteins decreased the phagocytosis as well as the chemotactic and random migrations of the cells, while preincubation with high density lipoproteins increased the same functions. No effects were seen with low density lipoproteins. It is suggested that disturbances in plasma lipoprotein pattern may affect the function of phagocytes.
生理浓度下不同的血浆脂蛋白组分对人嗜中性粒细胞的吞噬作用和迁移具有相反的影响。与极低密度脂蛋白预孵育半小时会降低细胞的吞噬作用以及趋化性迁移和随机迁移，而与高密度脂蛋白预孵育则会增强相同的功能。低密度脂蛋白未显示出作用。提示血浆脂蛋白模式的紊乱可能会影响吞噬细胞的功能。
