人体中的一氧化二氮与中性粒细胞趋化性

Nitrous oxide and neutrophil chemotaxis in man.

作者信息

Hill G E, English J B, Stanley T H, Kawamura R, Loeser E A, Hill H R

出版信息

Br J Anaesth. 1978 Jun;50(6):555-8. doi: 10.1093/bja/50.6.555.

DOI:10.1093/bja/50.6.555

Abstract

Inhalation of 60% nitrous oxide in oxygen by seven adult male volunteers for 60 min was found to increase significantly polymorphonuclear leuocyte (PMN) chemotaxis, but not to influence total white or PMN blood cell counts. Also, the addition or morphine 0.2 mg kg-1 i.v. during the breathing of nitrous oxide did not alter any variable. These results indicate that nitrous oxide and nitrous oxide incombination with morphine do not depress PMN chemotaxis.

摘要

七名成年男性志愿者吸入含60%氧化亚氮的氧气60分钟后，发现其多形核白细胞（PMN）趋化性显著增加，但对白细胞总数或PMN血细胞计数无影响。此外，在氧化亚氮吸入期间静脉注射0.2 mg/kg吗啡，也未改变任何变量。这些结果表明，氧化亚氮以及氧化亚氮与吗啡联合使用均不会抑制PMN趋化性。