去唾液酸免疫球蛋白和类风湿因子。
Asialylated immunoglobulins and rheumatoid factors.
作者信息
Duc Dodon M, Quash G A
出版信息
Rheumatol Int. 1983;3(3):97-100. doi: 10.1007/BF00541186.
PMID:6669869
Abstract
A covalently coupled IgG-latex reagent was instrumental in isolating rheumatoid factors (RF) from normal immunoglobulins in the sera of patients with rheumatoid arthritis. It was found that RF contained hyposialylated immunoglobulins of both IgG and IgM classes. This biochemical alteration might be relevant to understanding the etiopathogenesis of the disease.
摘要
一种共价偶联的IgG-乳胶试剂有助于从类风湿性关节炎患者血清中的正常免疫球蛋白中分离出类风湿因子（RF）。研究发现，RF含有IgG和IgM类的低唾液酸化免疫球蛋白。这种生化改变可能与理解该疾病的病因发病机制有关。
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