De Toma G, Marzano D, Salvatore P, Cerza F, De Cesare E, Giacovazzo M, Martelletti P, Antonucci M
Ital J Surg Sci. 1983;13(4):269-73.
Modifications in serum levels of creatine phosphokinase (CPK) lactic dehydrogenase (LDH), glutamic-oxalacetic-transaminases (GOT), glutamic-pyruvic-transaminases, L-gamma-glutamyl transferases, alkaline phosphatase, glycemia, serum nitrogen, creatinine, amylase, sodium and potassium were measured in dogs during experimentally induced acute mesenteric infarction, in the attempt to establish useful criteria for the early diagnosis of mesenteric infarction. Twelve dogs were studied, 6 being submitted to simple laparotomy and 6 to ligation of the superior mesenteric artery which caused mesenteric infarction. Venous blood samples were collected for 24 hours after surgery in all animals in order to detect any changes in the above-mentioned enzymatic and metabolic parameters. All animals were killed after the experiment and autopsy studies carried out. Animal with mesenteric infarction displayed a significant increase in serum total CPK, LDH, GOT and alkaline phosphatase. This observation may be useful in the diagnosis of acute mesenteric infarction.
在实验性诱导犬急性肠系膜梗死期间，测定了血清肌酸磷酸激酶（CPK）、乳酸脱氢酶（LDH）、谷草转氨酶（GOT）、谷丙转氨酶、L-γ-谷氨酰转移酶、碱性磷酸酶、血糖、血清氮、肌酐、淀粉酶、钠和钾水平的变化，试图建立早期诊断肠系膜梗死的有用标准。研究了12只犬，其中6只接受单纯剖腹术，6只接受肠系膜上动脉结扎术，后者导致肠系膜梗死。术后24小时内采集所有动物的静脉血样，以检测上述酶和代谢参数的任何变化。实验结束后处死所有动物并进行尸检研究。患有肠系膜梗死的动物血清总CPK、LDH、GOT和碱性磷酸酶显著升高。这一观察结果可能有助于急性肠系膜梗死的诊断。
