连续搅拌釜式反应器系统中的连续固定化酶促反应。

Consecutive immobilized enzymatic reactions in continuous stirred tank reactor systems.

作者信息

Lin S H

出版信息

Biophys Chem. 1978 May;8(2):105-10. doi: 10.1016/0301-4622(78)80001-5.

Abstract

The performance characteristics of two-enzyme reaction in a continuous stirred tank reactor (CSTR) are analytical investigated in this work. A model is formulated to describe the substrate concentration variations by taking into account the external and internal diffusion resistances. It is found that the reaction system exhibits the characteristics of reaction control or diffusion control depending on the operating conditions. The single CSTR model is also extended to describe the multiple CSTR system. The latter model enables the prediction of the number of CSTRs in series required to achieve a prescribed substrate conversion.

摘要

本文对连续搅拌釜式反应器（CSTR）中双酶反应的性能特征进行了分析研究。通过考虑外部和内部扩散阻力，建立了一个描述底物浓度变化的模型。结果发现，根据操作条件，反应系统呈现出反应控制或扩散控制的特征。单CSTR模型也被扩展以描述多个CSTR系统。后一个模型能够预测为实现规定的底物转化率所需串联的CSTR数量。