Vanprapar N, Chavalittamrong B, Chearskul S, Pimolpan V
Southeast Asian J Trop Med Public Health. 1983 Dec;14(4):488-90.
A seroepidemiology of measles hemagglutination inhibition antibody was studied in infants at birth to 8 months of age. It was found that at birth the antibody was greater than 1:8 in 56 of 64 newborns. At 2 and 4 months of age, 9 of 21 and 12 of 21 respectively had measles antibody titer less than 1:8, while at 8 months of age, only 1 of 6 had the antibody titer greater than 1:8. It shows that the maternal measles antibody can protect the infant at young age and the decrease in antibodies occur as the child grows. The measles vaccine should be given when the maternal passive immunity of measles disappears. This study indicates that the optimal age to recommend measles vaccination should be at the age of 9 months.
对出生至8个月大的婴儿进行了麻疹血凝抑制抗体的血清流行病学研究。结果发现，64名新生儿中，56名在出生时抗体大于1:8。在2个月和4个月大时，21名婴儿中分别有9名和12名麻疹抗体滴度低于1:8，而在8个月大时，6名婴儿中只有1名抗体滴度大于1:8。这表明母体麻疹抗体可在婴儿年幼时提供保护，且随着孩子成长抗体水平会下降。当母体麻疹被动免疫消失时应接种麻疹疫苗。本研究表明，推荐麻疹疫苗接种的最佳年龄应为9个月。
