Abdurrahman M B, Greenwood B M, Olafimihan O, Whitle H C
Afr J Med Med Sci. 1982 Sep;11(3):113-5.
Measles antibody (HAI) titres were measured in healthy Nigerian infants at birth and at 3, 6 and 9 months of age. At birth only one baby out of thirty-five had HAI titre of less than 1:4, but at 3 months of age titres had fallen to this level in 33% of children. The percentage increased further to 78.6% at 6 months of age. At 9 months, nine out of twenty-seven (33%) infants had HAI titre of 1:16 and above, suggesting recent measles infection or immunization. The rapid fall in HAI titres up to 6 months could explain the occurrence of measles in early age in tropical countries. We recommend that children in Nigeria be immunized at 7-8 months of age.
对尼日利亚健康婴儿在出生时以及3个月、6个月和9个月大时的麻疹抗体（血凝抑制试验，HAI）滴度进行了测量。出生时，35名婴儿中只有1名的HAI滴度低于1:4，但在3个月大时，33%的儿童滴度降至该水平。6个月大时，这一比例进一步升至78.6%。9个月大时，27名婴儿中有9名（33%）的HAI滴度为1:16及以上，提示近期有麻疹感染或免疫接种。6个月前HAI滴度的快速下降可以解释热带国家幼儿期麻疹的发生情况。我们建议尼日利亚的儿童在7至8个月大时进行免疫接种。
