Harry T O, Ogunmekan D A
Trop Geogr Med. 1981 Dec;33(4):375-8.
The decline of maternally acquired haemagglutination inhibiting antibodies against measles virus in Nigerian children born in Lagos was studied. At birth all the 303 children whose cord blood serum was tested had measurable antibodies. The antibody titre remained detectable in all the children up to four months of age, and in over 90% at five months of age. At six months 65% of the children were without detectable antibodies. At seven and eight months the proportion of children without measurable antibodies was reduced to 50% and 42% respectively, indicating a slight but progressive improvement in the immune status of the children. These findings provide a serological basis for starting anti-measles immunization of Nigerian children at six months.
对出生于拉各斯的尼日利亚儿童中，母体获得的抗麻疹病毒血凝抑制抗体的下降情况进行了研究。在出生时，检测脐带血血清的303名儿童均有可测量的抗体。所有儿童在4个月龄前抗体滴度均可检测到，5个月龄时超过90%的儿童仍可检测到。6个月时，65%的儿童检测不到抗体。7个月和8个月时，无可测量抗体的儿童比例分别降至50%和42%，表明儿童的免疫状态有轻微但持续的改善。这些发现为尼日利亚儿童在6个月时开始进行抗麻疹免疫接种提供了血清学依据。
