从格林氏瘤中分离并鉴定延伸因子EF-2
Isolation and characterization of elongation factor EF-2 from Guerin tumour.
作者信息
Jabłonowska K, Kopacz-Jodczyk T, Niedźwiecka J, Gałasiński W
出版信息
Acta Biochim Pol. 1983;30(3-4):381-8.
PMID:6673428
Abstract
A homogeneous preparation of EF-2 from Guerin tumour cells was obtained. Its Mr (68 000), pI (6.5), optimum pH (7.0) and amino acid composition are very close to those of rat liver elongation factor. EF-2 from Guerin tumour cells is active in the heterologous liver - tumour system, although half as effective as in the homologous system.
摘要
从格林氏瘤细胞中获得了一种均一的EF-2制剂。其相对分子质量（68 000）、等电点（6.5）、最适pH（7.0）和氨基酸组成与大鼠肝脏延伸因子非常接近。格林氏瘤细胞中的EF-2在异源肝脏-肿瘤系统中具有活性，尽管其效力仅为同源系统中的一半。
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