Pye A
Br J Audiol. 1978 May;12(2):51-3. doi: 10.3109/03005367809078853.
Guinea pigs were used to test acoustic trauma effects from doubling the exposure time. Previously, two frequencies (20 kHz and 4 kHz) were used in conjunction with each other (ie double exposure) to see whether a prior exposure of the cochlea to one frequency would alter the extent of damage caused by a secondary frequency, when compared with damage caused by either frequency alone. A reduced area of damage was attained after double exposures. To complete the series, the same two frequencies were used separately, but the exposure time was doubled. The results from the 20 kHz series surprisingly indicated that a reduced area of damage was obtained after doubling the exposure time. No significant differences were found in the 4 kHz series.
豚鼠被用于测试将暴露时间加倍所产生的听觉创伤效应。此前,使用了两个频率(20千赫兹和4千赫兹)相互结合(即双重暴露),以观察耳蜗预先暴露于一个频率时,与单独由任一频率造成的损伤相比,是否会改变由第二个频率造成的损伤程度。双重暴露后损伤面积减小。为完善该系列实验,使用相同的两个频率分别进行实验,但将暴露时间加倍。20千赫兹系列的结果出人意料地表明,暴露时间加倍后损伤面积减小。在4千赫兹系列中未发现显著差异。