Haneberg B, Tønjum T, Rodahl K, Gedde-Dahl T W
NIPH Ann. 1983 Dec;6(2):169-73.
In a prospective study of 115 patients with systemic meningococcal disease, 61 control patients and 293 population controls, environmental and other factors which preceded the illness and which might have influenced the acquisition and case fatality rate of the meningococcal disease were investigated. Passive smoking in children under 12 year of age, stressful events, and symptoms and signs of preceding illness within the last two weeks were significantly more frequent in meningococcal patients than among the population controls. In contrast, those patients who had been exposed to stressful events, or who had symptoms or signs of ill-health preceding the meningococcal disease, had significantly reduced case fatality rates as compared to those who had not had any such experiences. Passive smoking remains a factor of great interest for further studies and intervention.
在一项针对115例系统性脑膜炎球菌病患者、61例对照患者和293名人群对照的前瞻性研究中，对疾病发生前可能影响脑膜炎球菌病感染率和病死率的环境及其他因素进行了调查。12岁以下儿童的被动吸烟、应激事件以及过去两周内前驱疾病的症状和体征在脑膜炎球菌病患者中比在人群对照中更为常见。相比之下，与未经历过此类情况的患者相比，那些经历过应激事件或在患脑膜炎球菌病之前有健康不佳症状或体征的患者病死率显著降低。被动吸烟仍是进一步研究和干预的重要关注点。
