de Carvalho D G, Ribeiro T de C, Barbosa A J, Castro L de P
Arq Gastroenterol. 1983 Jul-Sep;20(3):85-91.
A prospective study of the effects of maximal doses of betazol hydrochloride ( Histalog ) on the endoscopic and histologic findings of the gastric mucosa of volunteers was made. Of the 11 patients examined, no alteration was seen on gastroscopic examination after Histalog in three, slight to moderate congestion of the mucosa in six and scattered oozing bleeding points in two. The study of the histologic findings revealed no statistical significant difference in the recurrence of erosion, hemorrhage and edema in the antrum and body gastric mucosa, before and after the administration of Histalog . It was concluded that maximal doses of Histalog cause no significant hemorrhage in the mucosa of the stomach and that the brown colour frequently seen in the gastric secretions of the final portions of a Histalog test is to be attributed to trauma to the mucosa by the nasogastric tube and to Histalog induced congestion of the mucosa.
对最大剂量的盐酸倍他唑（组胺胃复康）对志愿者胃黏膜内镜及组织学表现的影响进行了一项前瞻性研究。在接受检查的11名患者中，服用组胺胃复康后，胃镜检查显示3名患者无改变，6名患者黏膜有轻度至中度充血，2名患者有散在渗血点。组织学表现研究显示，服用组胺胃复康前后，胃窦和胃体黏膜糜烂、出血及水肿的复发情况无统计学显著差异。得出的结论是，最大剂量的组胺胃复康不会导致胃黏膜显著出血，组胺胃复康试验最后部分胃分泌物中常见的棕色应归因于鼻胃管对黏膜的损伤以及组胺胃复康引起的黏膜充血。
