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关节软骨表面:免疫组织学研究。

Surface of articular cartilage: immunohistological studies.

作者信息

Duance V C

出版信息

Cell Biochem Funct. 1983 Oct;1(3):143-4. doi: 10.1002/cbf.290010304.

DOI:10.1002/cbf.290010304
PMID:6678620
Abstract

Using several physical techniques the surface of articular cartilage has been reported to be structurally different from the deeper layers. In this paper using immunohistochemical methods, the surface has been shown to contain a characteristically different collagen, Type I in contrast to Type II which is the major collagen of cartilage. These results support previous proposals for a surface layer, or lamina splendens, the presence of which would be of considerable importance in understanding the degradation of cartilage in arthritides.

摘要

据报道,使用多种物理技术观察到关节软骨表面在结构上与较深层不同。在本文中,通过免疫组织化学方法显示,表面含有一种特征性不同的胶原蛋白,即I型胶原,而软骨的主要胶原蛋白是II型胶原。这些结果支持了先前关于表面层或光彩层的提议,其存在对于理解关节炎中软骨的降解具有相当重要的意义。

相似文献

1
Surface of articular cartilage: immunohistological studies.关节软骨表面:免疫组织学研究。
Cell Biochem Funct. 1983 Oct;1(3):143-4. doi: 10.1002/cbf.290010304.
2
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Mechanical Cues: Bidirectional Reciprocity in the Extracellular Matrix Drives Mechano-Signalling in Articular Cartilage.力学线索:细胞外基质中的双向相互作用驱动关节软骨中的机械信号转导。
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Culture of human bone marrow-derived mesenchymal stem cells on of poly(L-lactic acid) scaffolds: potential application for the tissue engineering of cartilage.
人骨髓间充质干细胞在聚(L-乳酸)支架上的培养:软骨组织工程的潜在应用。
Knee Surg Sports Traumatol Arthrosc. 2013 Aug;21(8):1737-50. doi: 10.1007/s00167-012-2148-6. Epub 2012 Aug 4.
4
Type III collagen in normal human articular cartilage.正常人体关节软骨中的III型胶原蛋白。
Histochem J. 1994 May;26(5):412-6. doi: 10.1007/BF00160053.