Ivanov K P, Chuĭkin A E, Berkos O V, Stolbov A L
Fiziol Zh SSSR Im I M Sechenova. 1983 Jul;69(7):942-8.
Energy expenditure and O2 consumption, the tidal volume of cardiac output (Q) and the respiration (VE), the arterio-venous difference in O2 content, the arterial and venous blood gases, and the survival of animals in graded decrease of the hemoglobin concentration in the vascular bed (hemodilution) were studied in anesthetized Wistar rats as well as the values of oxygen available in the brain tissue. The animals were shown to maintain the initial level of energy expenditure by means of the Q increase up to reducing the hemoglobin concentration from 16.2 g/dl to 4.9 g/dl (hematocrit 12.9%). The elements of oxygen insufficiency, however, as measured by the Q and VE responses as well as by changes in oxygen available in mixed venous blood and in brain tissue, become evident yet in early stages of the hemodilution.
在麻醉的Wistar大鼠中，研究了能量消耗和氧气消耗、心输出量（Q）和呼吸（VE）的潮气量、氧含量的动静脉差异、动脉和静脉血气，以及血管床中血红蛋白浓度分级降低（血液稀释）时动物的存活情况，同时还研究了脑组织中可利用氧的值。结果显示，动物通过增加Q来维持能量消耗的初始水平，直至血红蛋白浓度从16.2 g/dl降至4.9 g/dl（血细胞比容12.9%）。然而，通过Q和VE反应以及混合静脉血和脑组织中可利用氧的变化来衡量的氧不足因素，在血液稀释的早期阶段就已明显显现。
