[3α-³H]β-谷甾醇的简便合成。
A facile synthesis of [3 alpha-3 H]beta -sitosterol.
作者信息
Dayal B, Salen G, Tint G S, Biswas C
出版信息
Steroids. 1983 Dec;42(6):635-40. doi: 10.1016/0039-128x(83)90127-7.
PMID:6680934
Abstract
Direct oxidation of the parent sterol using CrO3 provided (24R)-24-ethyl-5-cholesten-3-one which on treatment with NaBT4 gave [3 alpha-3 H] (24R)-24-ethyl-5-cholesten-3 beta-ol. Purification at each stage afforded samples which were compared spectrally with the corresponding cholesterol series compounds.
摘要
使用三氧化铬对母体甾醇进行直接氧化得到(24R)-24-乙基-5-胆甾烯-3-酮，其用硼氢化钠处理后得到3α-³H-24-乙基-5-胆甾烯-3β-醇。每个阶段的纯化得到的样品与相应的胆固醇系列化合物进行光谱比较。
Zotero 插件