Kaplan M
Am J Dis Child. 1983 Feb;137(2):177-81.
Although the presence of fetal breathing movements (FBMs) has been suspected for almost a century, the major advances in the field were made during the last decade. Experimental animal techniques of detection include instrumentation of fetuses with electronic recording equipment. Human studies use more indirect, although no less accurate, A-mode or real-time B-scan ultrasonography in the recording of FBMs. The fetus does not make breathing movements continuously; however, there are periods of FBMs interspersed with periods of apnea. Inherent to FBMs is a diurnal variation. Hypoxia and hypoglycemia diminish FBMs, while hypercarbia and hyperglycemia have the opposite effect. Caffeine, barbiturates, and general anesthetics modify FBMs by their influence on the CNS. Preliminary studies have shown the presence of FBMs to indicate a state of fetal well-being. Possibly, in the future, testing for FBMs may become a useful clinical tool in the identification of the fetus at risk.
尽管人们怀疑胎儿呼吸运动(FBMs)的存在已有近一个世纪,但该领域的重大进展是在过去十年取得的。检测的实验动物技术包括用电子记录设备对胎儿进行仪器监测。人体研究在记录FBMs时使用更间接但同样准确的A型或实时B超超声检查。胎儿并非持续进行呼吸运动;然而,FBMs期间会穿插有无呼吸期。FBMs存在昼夜变化。缺氧和低血糖会减少FBMs,而高碳酸血症和高血糖则有相反的作用。咖啡因、巴比妥类药物和全身麻醉剂通过对中枢神经系统的影响来改变FBMs。初步研究表明,FBMs的存在表明胎儿处于良好状态。未来,检测FBMs可能会成为识别高危胎儿的一种有用的临床工具。