Saito M, Ibuka N
Physiol Behav. 1983 Jan;30(1):87-92. doi: 10.1016/0031-9384(83)90042-2.
The circadian feeding rhythm and food intake under restricted feeding conditions, including adiurnal feeding cycles, were examined in rats with bilateral lesions of the suprachiasmatic nucleus (SCN). Although rats with SCN-lesions ate nearly as much food per day as those with control-lesions, their feeding pattern did not show circadian rhythmicity. When rats with control-lesions were fed for 5 hr once every 20 hr or for 7 hr once every 28 hr, they ate less than when they were fed for 6 hr once every 24 hr, probably due to some effect of desynchronization between the feeding cycle and an endogenous circadian oscillator. Decreased food intake under adiurnal feeding cycles was also observed in rats with SCN-lesions as in those with control-lesions. It is suggested that the circadian rhythm entrained by food is related to an endogenous time-keeping system that does not include the SCN.
在视交叉上核（SCN）双侧损伤的大鼠中，研究了包括隔日进食周期在内的限制进食条件下的昼夜进食节律和食物摄入量。尽管SCN损伤的大鼠每天的食物摄入量与对照损伤的大鼠几乎相同，但其进食模式并未表现出昼夜节律性。当对照损伤的大鼠每20小时进食一次，每次5小时，或每28小时进食一次，每次7小时时，它们的进食量比每24小时进食一次，每次6小时时要少，这可能是由于进食周期与内源性昼夜节律振荡器之间的某种不同步效应所致。与对照损伤的大鼠一样，SCN损伤的大鼠在隔日进食周期下也观察到食物摄入量减少。这表明由食物诱导的昼夜节律与一个不包括SCN的内源性计时系统有关。
