双胞胎调查在畸形研究中的价值。
The value of twin surveys in the study of malformations.
作者信息
Cameron A H, Edwards J H, Derom R, Thiery M, Boelaert R
出版信息
Eur J Obstet Gynecol Reprod Biol. 1983 Feb;14(5):347-56. doi: 10.1016/0028-2243(83)90011-4.
PMID:6682384
Abstract
Congenital malformations have been investigated in a consecutive series of 445 monozygotic twin pairs coming from two twin surveys numbering 1,424 pairs. Concordant malformations were found in 6 pairs, discordant in 20 pairs. The significance of these findings is briefly discussed. The methodology of the prospective twin studies is described. The diagnosis of zygosity is based on sex, structure of placental membranes, blood groups and enzyme systems of the blood and placenta.
摘要
对来自两项共1424对双胞胎调查中的445对同卵双胞胎进行了先天性畸形调查。发现6对有一致的畸形，20对有不一致的畸形。简要讨论了这些发现的意义。描述了前瞻性双胞胎研究的方法。合子性的诊断基于性别、胎盘膜结构、血型以及血液和胎盘的酶系统。
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