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[念珠菌属不同种酵母的蛋白质和抗原谱]

[Protein and antigenic spectrum of different species of yeasts of the genus Candida].

作者信息

Mishneavskĭ N V, Tsinberg M B, Obvintsev V K

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1976(12):91-4.

PMID:66829
Abstract

The methods of electrophoresis in polyacrylamide gel, immunoelectrophoresis and immunoprecipitation were applied to the study of the protein and antigenic spectra of different species of Candida yeasts. It was revealed that for the majority of the yeast species the prevalence of proteins of definite fractions was characteristic. C. albincans displayed a marked (in comparison with the nonpathogenic species) content of proteins of proteins of group b. The most pronounced antigenic properties in C. albicans and C. tropicalis were possessed by the proteins of the basic character. C. albicans and C. tropicalis yeasts were characterized by similar antigenic spectra, whereas the C. crusei species showed the least affinity with the C. albicans.

摘要

采用聚丙烯酰胺凝胶电泳、免疫电泳和免疫沉淀法对不同种类念珠菌酵母的蛋白质和抗原谱进行了研究。结果表明,对于大多数酵母菌种来说,特定组分蛋白质的优势是其特征所在。白色念珠菌显示出(与非致病菌种相比)b组蛋白质含量显著。白色念珠菌和热带念珠菌中碱性蛋白质具有最明显的抗原特性。白色念珠菌和热带念珠菌酵母具有相似的抗原谱,而克鲁斯念珠菌与白色念珠菌的亲缘关系最弱。

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