Meerson F Z, Dosmagambetova R S
Kardiologiia. 1983 Mar;23(3):20-6.
The contractility of the right atrium, a heart region known to be unaffected by ischemia, was studied in rats with experimental left ventricular infarction. The study of the isolated atrium established reduced right-atrial myocardial tensility, depressed Starling's curve and, as a result, a two-fold decrease in maximum systolic tension within 24 hours after the coronary occlusion. The resistance of atrial myocardium to hypoxia and calcium excess was also diminished. This set of changes could be reproduced completely in the absence of myocardial infarction through emotional-painful stress, on one hand, and it could be to a great extent prevented by a beta-adrenoreceptor blocker propranolol, on the other hand, i.e. a stress-related origin is postulated.
在患有实验性左心室梗死的大鼠中，对右心房（已知不受局部缺血影响的心脏区域）的收缩性进行了研究。对离体心房的研究表明，右心房心肌张力降低，斯塔林曲线压低，结果在冠状动脉闭塞后24小时内最大收缩张力下降了两倍。心房心肌对缺氧和钙过量的耐受性也降低。这一系列变化一方面可以通过情绪痛苦应激在无心肌梗死的情况下完全重现，另一方面可以在很大程度上被β-肾上腺素能受体阻滞剂普萘洛尔阻止，即假定其起源与应激有关。
