Chapman H D
Vet Parasitol. 1983 Feb;12(1):45-50. doi: 10.1016/0304-4017(83)90086-9.
Twenty-four field isolates of Eimeria spp. which included Eimeria acervulina, E. praecox and E. mivati were tested for sensitivity to arprinocid included in the diet at 60 ppm. Twelve isolates from sites where arprinocid had been use for 5-7 successive flocks were resistant to the drug, whereas 12 isolates from sites where arprinocid had never been used were sensitive. These results indicate that resistance had been acquired as a result of the use of arprinocid in the field.
对24株艾美耳球虫属的田间分离株进行了测试,这些分离株包括堆型艾美耳球虫、早熟艾美耳球虫和米氏艾美耳球虫,检测它们对日粮中60 ppm的阿普林诺西德的敏感性。来自连续5至7批鸡群使用过阿普林诺西德的地点的12株分离株对该药物具有抗性,而来自从未使用过阿普林诺西德的地点的12株分离株则敏感。这些结果表明,田间使用阿普林诺西德导致了抗药性的产生。