Pandolfi F, Luzi G, Tozzi C, Aiuti F
Acta Haematol. 1977;57(5):257-65. doi: 10.1159/000207889.
A serum against human lymphoblastic leukemia cells was obtained inoculating rabbits. We studied the specificity of the serum before and after particular absorptions in various clinical conditions. The serum was cytotoxic against many cases of acute lymphoblastic leukemia, against continuously cultured Burkitt's lymphoma cells and against chronic myelogenous leukemia in blast crisis. On the contrary, the serum was not cytotoxic against lymphocytes of normal donors, acute lymphoblastic leukemia in remission and other lymphoproliferative disorders.
通过给兔子接种获得了一种抗人淋巴细胞白血病细胞的血清。我们研究了在各种临床情况下特定吸收前后血清的特异性。该血清对许多急性淋巴细胞白血病病例、连续培养的伯基特淋巴瘤细胞以及处于原始细胞危象的慢性粒细胞白血病具有细胞毒性。相反，该血清对正常供体的淋巴细胞、缓解期的急性淋巴细胞白血病以及其他淋巴增殖性疾病没有细胞毒性。
