Ahmed H A, Touw J, Stoner G L, Belehu A
Int J Lepr Other Mycobact Dis. 1983 Mar;51(1):22-8.
IgA levels in nasal washings and saliva were determined in leprosy patients and healthy controls. In addition, serum levels of IgA, IgG, and IgM and total serum protein were analyzed. IgA levels in the nasal washings, but not in the salivas, were elevated significantly in the borderline (BL) and lepromatous (LL) groups. In the tuberculoid (TT) and borderline tuberculoid (BT) groups, the IgA levels in both the nasal washings and salivas did not differ from the controls. Total protein was also elevated in the nasal washings in the BL and LL groups. Thus, the IgA expresses as mg/mg protein did not differ significantly from the control group. However, in individual patients the levels of IgA and total protein were not correlated in either the nasal washings or the salivas. The high serum immunoglobulin and protein levels were in accord with the findings of most other workers.
测定了麻风患者和健康对照者鼻腔灌洗液和唾液中的IgA水平。此外，还分析了血清中IgA、IgG和IgM水平以及总血清蛋白。在界线类（BL）和瘤型（LL）组中，鼻腔灌洗液中的IgA水平显著升高，但唾液中的IgA水平未升高。在结核样型（TT）和界线类偏结核样型（BT）组中，鼻腔灌洗液和唾液中的IgA水平与对照组无差异。BL和LL组鼻腔灌洗液中的总蛋白也升高。因此，以mg/mg蛋白表示的IgA与对照组无显著差异。然而，在个体患者中，鼻腔灌洗液或唾液中IgA水平与总蛋白水平均无相关性。血清免疫球蛋白和蛋白水平升高与大多数其他研究人员的发现一致。
