Labbe R, Firl A, Mufson E J, Stein D G
Science. 1983 Jul 29;221(4609):470-2. doi: 10.1126/science.6683427.
Frontal cortex and cerebellar tissue from fetal rats was implanted into the damaged frontal cortex of adults. Cognitive deficits in spatial alternation learning that follow bilateral destruction of medial frontal cortex were reduced in rats with frontal cortex implants but not in those with implants of cerebellum. Histological evaluation showed that connections were made between the frontal cortex implants and host brain tissue.
将胎鼠的额叶皮质和小脑组织植入成年大鼠受损的额叶皮质。双侧内侧额叶皮质破坏后出现的空间交替学习认知缺陷,在植入额叶皮质的大鼠中有所减轻,但在植入小脑的大鼠中则没有。组织学评估显示,额叶皮质植入物与宿主脑组织之间建立了连接。