Francaviglia N, Silvestro C, Carta F, Davini V, Perria C, Scaricabarozzi I, Cipolla P V
Clinica Neurochirurgica, Università di Genova, Italy.
Acta Neurochir (Wien). 1990;102(1-2):62-8. doi: 10.1007/BF01402188.
This report concerns 23 patients, the majority of whom are suffering from low back and chest pain caused by chest, urological or gynaecological cancer. These patients were treated with subarachnoid buprenorphine, administered in a single bolus or by slow infusion from micropumps, at a daily dose adapted to patients need (0.06-0.15 mg). The painful symptomatology was successfully controlled in all the cases treated, allowing the patients to live a virtually normal life. In no cases was respiratory depression or tolerance observed.
本报告涉及23名患者，其中大多数人患有由胸部、泌尿系统或妇科癌症引起的腰背痛和胸痛。这些患者接受了蛛网膜下腔注射丁丙诺啡治疗，通过单次推注或微量泵缓慢输注，每日剂量根据患者需求调整（0.06 - 0.15毫克）。所有接受治疗的病例中，疼痛症状均得到成功控制，使患者能够过上几乎正常的生活。未观察到呼吸抑制或耐受性的情况。
